It is surely the nemesis of unbelievers.

And indeed it is a despair for the disbelievers.

Surely it is a sorrow to the unbelievers;

yet, behold, this [rejection] will indeed become a source of bitter regret for all who deny the truth [of God's revelation] –

And verily it shall be an occasion of anguish Unto the infidels.

And indeed it (this Quran) will be an anguish for the disbelievers (on the Day of Resurrection).

And it is surely a source of grief for the unbelievers.

And it is surely a source of grief for the unbelievers.

And it is a source of regret for the unbelievers.

And it is a source of regret for the unbelievers.

and it will surely be a source of regret for the disbelievers.

and surely it will be a cause of regret for the unbelievers.

And indeed it will be an anguish for the disbelievers.

And lo! it is indeed an anguish for the disbelievers.

And indeed it will be a [matter of] regret for the faithless.

Indeed, it is a sorrow to the unbelievers

And indeed, it will be [a cause of] regret upon the disbelievers.

and (on the Day of Judgment) this will be a great source of regret for the unbelievers.

And most surely it is a great grief to the unbelievers.

Wainnahu lahasratun AAala alkafireena

wa-innahu laḥasratun ʿalā l-kāfirīna

it will be a source of bitter regret for those who deny the truth --

But truly (Revelation) is a cause of sorrow for the Unbelievers.